Janet Simons

Medical Biochemist
Site Medical Lead, Pre and Post Analytical

"Medicine is a science of uncertainty and an art of probability." - Sir William Osler


Following my Bachelor’s of Science in Honours Biochemistry from the University of Waterloo, I completed my medical school, residency training in Internal Medicine, and fellowship in Medical Biochemistry at McMaster University. After my fellowship, I moved to Vancouver to join the Department of Pathology and Laboratory Medicine at St. Paul's Hospital.

In addition to my laboratory practice, I continue to enjoy clinical work in Internal Medicine. I am also involved in the leadership of the PHC Clinical Informatics program as Co-Medical Director, and the Medicine, Older Adult and Palliative Care program as Physician Program Director.

I am particularly interested in helping both the clinical services and the laboratory increase efficiency by improving communication and achieving better mutual understanding. I am a strong advocate for appropriate test utilization and high-value care. When not in the hospital, I enjoy cycling, hiking, and exploring Vancouver's restaurant scene.

Academic Background

  • BSc Hons Biochemistry, University of Waterloo
  • MD, McMaster University
  • FRCPC, Internal Medicine
  • FRCPC, Medical Biochemistry

Expertise / Research Interests

  • Cardiac Biomarkers
  • Lipids
  • Test Utilization
  • Clinical Informatics
  • Clinical Practice Guidelines

Teaching Interests

  • Clinical chemistry
  • Optimizing diagnostic pathways
  • Myocardial infarction
  • Laboratory utilization

Selected Publications

  • Chami N, Simons J, Sweetman A, Don-Wauchope AC. Rates of inappropriate laboratory test utilization in Ontario. Clin Biochem, 2017
  • Simons J, Don-Wauchope AC. Evaluation of natriuretic peptide recommendations in heart failure clinical practice guidelines. Clin Biochem 2016, 49(1):8-15.
  • Simons J, Don-Wauchope AC.  Reshaping Recommendations: Making clinical practice guidelines work for pathologists. The Pathologist 2014, 4:28-32.
  • Simons J, Beach L, Clark L, Kavsak PA. Matrix and bilirubin interference for high-sensitivity cardiac troponin I. Clin Chim Acta 2015, 442:49-51.
  • Simons J, Holbrook AM, Don-Wauchope AC. Successful reintroduction of statin therapy after statin-associated rhabdomyolysis. Journal of Clinical Lipidology 2015, 9(4):594-6.


Department of Pathology and Laboratory Medicine
St. Paul's Hospital, 1081 Burrard St
Vancouver, BC V6Z 1Y6