Janet Simons

Medical Biochemist
Site Medical Lead, Pre and Post Analytical

"Medicine is a science of uncertainty and an art of probability." - Sir William Osler


I grew up in Kingston, Ontario, but also spent significant portions of my childhood in New York City, the Netherlands, and Belgium. Following my Bachelor’s of Science in Honours Biochemistry from the University of Waterloo, I completed my medical school and residency training in Internal Medicine and Medical Biochemistry at McMaster University. After my residency training, I moved to Vancouver to join the Department of Pathology and Laboratory Medicine at St. Paul's Hospital.

In addition to my laboratory practice, I continue to enjoy clinical work in Internal Medicine. I am particularly interested in helping both the clinical services and the laboratory increase efficiency by improving communication and achieving better mutual understanding. When not in the hospital, I enjoy cycling, hiking, and exploring Vancouver's restaurant scene.

Academic Background

  • BSc Hons Biochemistry, University of Waterloo
  • MD, McMaster University
  • FRCPC, Internal Medicine
  • FRCPC, Medical Biochemistry

Expertise / Research Interests

  • Cardiac Biomarkers
  • Lipids
  • Test Utilization
  • Clinical Practice Guidelines

Teaching Interests

  • Clinical chemistry
  • Optimizing diagnostic pathways
  • Myocardial infarction
  • Laboratory utilization

Selected Publications

  • Chami N, Simons J, Sweetman A, Don-Wauchope AC. Rates of inappropriate laboratory test utilization in Ontario. Clin Biochem, 2017
  • Simons J, Don-Wauchope AC. Evaluation of natriuretic peptide recommendations in heart failure clinical practice guidelines. Clin Biochem 2016, 49(1):8-15.
  • Simons J, Don-Wauchope AC.  Reshaping Recommendations: Making clinical practice guidelines work for pathologists. The Pathologist 2014, 4:28-32.
  • Simons J, Beach L, Clark L, Kavsak PA. Matrix and bilirubin interference for high-sensitivity cardiac troponin I. Clin Chim Acta 2015, 442:49-51.
  • Simons J, Holbrook AM, Don-Wauchope AC. Successful reintroduction of statin therapy after statin-associated rhabdomyolysis. Journal of Clinical Lipidology 2015, 9(4):594-6.


Department of Pathology and Laboratory Medicine
St. Paul's Hospital, 1081 Burrard St
Vancouver, BC V6Z 1Y6