Mari L. DeMarco
Clinical Chemist
Biography 
I received a BSc in Honours Biochemistry and a minor in Mathematics from Mercyhurst University. I earned a PhD from the University of Washington, as part of the Biomolecular Structure and Design Program. I subsequently completed a Clinical Chemistry fellowship at Washington University School of Medicine in St Louis. For my PhD thesis I explored protein misfolding pathways and focused on the pathological mechanisms (misfolding, aggregation and replication) involved in human prion diseases. This interest in amyloidosis and neurodegeneration has carried over to my clinical work, where I am pursuing assay development to support diagnostic and research efforts in these areas. Another active area of research is the application of mass spectrometry to tackle challenging diagnostic problems in Laboratory Medicine.
Academic Background
- BSc Honors, Biochemistry (major), Mathematics (minor), Mercyhurst University
- PhD, Department of Medicinal Chemistry, Biomolecular Structure and Design Program, University of Washington
- Clinical Chemistry Fellowship, Washington University School of Medicine
Expertise / Research Interests
- Clinical Chemistry
- Biochemistry
- Mass Spectrometry
- Structural Biology
Teaching Interests
- Clinical Chemistry
- Biochemistry
- Mass Spectrometry
- Structural Biology
Selected Publications
https://www.demarcolab.ca/publications
Contact
Department of Pathology and Laboratory Medicine
St. Paul's Hospital, 1081 Burrard St.
Vancouver, BC V6Z 1Y6
604-682-2344
External Links / Resources
DeMarco Lab website: https://www.demarcolab.ca/
