Transcatheter Aortic Heart Valves

November 15, 2018

Dr. Stephanie Sellers, in collaboration with Dr. Michael Seidman (Pathology and Laboratory Medicine) and Dr. Jonathan Leipsic and team (Department of Radiology) was the lead investigator in this study which examined correlates of leaflet thickening and structural valve degeneration (SVD) in a systematic analysis, using a multimodal ex vivo analysis of explanted transcatheter heart valves.

The histopathological analysis provides important insight into the pattern of valve thrombus, fibrosis and calcification which will help inform future imaging studies aimed at defining the potential link between valve thrombus and SVD.