Undetected Hepatocellular Carcinoma in Patients Undergoing Liver Transplantation

November 8, 2017

Dr. Wei Xiong, in the Division of Anatomic Pathology, is the first author on a recent publication in the American Journal of Surgical Pathology "Radiologically undetected hepatocellular carcinoma in patients undergoing liver transplantation: an immunohistochemical correlation with LI-RADS score."

This study found that small tumor size (<2 cm), low-grade histologic differentiation, and low microvessel density were factors contributing to detection failure of hepatocellular carcinoma in the pretransplant CT-imaging studies.  The observations emphasize the evolving importance of the Liver Imaging Reporting and Data System (LI-RADS) assessment in liver transplant candidates.